Sudden Death of Young Athletes - Endotoxin Link
Hidden behind paywalls, much can be found about Endotoxemia induced by vigorous exercise in people otherwise considered fit and healthy who are at risk of dropping dead from Heart Failure
Before the Covid19 pandemic and mass jabbing frenzy, young athletes were known to die on the sports field or shortly after returning home from competition.1
The reason can be traced to careful studies in Humans published in 1988 by South African researchers Bosenberg et al.2
They studied 18 Male triathletes competing in an ultradistance triathlon. Their mean plasma Endotoxin (Lipopolysaccharide, LPS) concentrations increased from 0.081 to 0.294 nanogram/ml, and their mean plasma anti-Endotoxin (anti-LPS) immunoglobulin G (IgG) concentrations decreased from 67.63 to 38.99 picogram/ml. Both pretriathlon plasma Endotoxin and anti-Endotoxin IgG levels were directly related to the intensity of training. They proposed that training-induced stress led to some leakage of Endotoxin, leading to Tolerance. They were unaware that in the same year this was elegantly proven to be true.3
I have covered various aspects of Endotoxin Heart damage and the interested reader will find numerous references to direct attack on Cardiomyocytes4, Pulmonary Hypertension5, Endotoxin Induced Myocarditis6, Atrial Fibrillation, the most common form of Tachycardia7 and why young Males are more vulnerable8.
I will add more about anti-Endotoxin immunoglobulin G later.
Laura Beil. 2014. https://www.sciencenews.org/article/sudden-death
Bosenberg AT, et al. 1988. Strenuous exercise causes systemic endotoxemia. https://journals.physiology.org/doi/abs/10.1152/jappl.1988.65.1.106
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