Endotoxin in mRNA Jabs attacks your P450 Cytochrome Defences
Our Liver does most of the Detoxification of Drugs and its capacity to protect is severely damaged by the Endotoxin Contamination in all mRNA vials.
Thanks to my friend Chris Edwards, I was prompted to look at the impact of the Endotoxin in mRNA jabs on the very complicated Cytochrome enzyme system that does most of the work in detoxifying drugs and natural poisons that enter our bodies.
I will publish as an outline and build it as people contribute their expert knowledge and references.
Pfizer excluded people taking drugs related to P450 from its Process 1 Clinical Trial
During the Pfizer Clinical Trials which used the Process 1 method to make the Drug Substance, we know from the protocols they would not use subjects who were on drugs that inhibited or enhanced Cytochrome family P450.1
Regulatory Authorities concerned about P450
The EMA and New Zealand regulatory authorities main concern about the Pfizer mRNA jabs related to Cytochrome P450 was possible formation of carcinogenic Nitrosamines, which they considered highly unlikely due to the limited access of the enzymes to the very large molecule Spike Protein mRNA molecule.
Pfizer Paxlovid impacts P450
P450 is a major concern in Paxlovid metabolism.2
Sex differences in Adverse Effects could relate to P450
There are sex differences in the Cytochrome P450 metabolism of toxins.
Making inroads into Jab effects on P450 is a Challenge
It is a huge subject with more than 300,000 distinct CYP proteins known.
Useful introductions here :
http://www.reactome.org/content/detail/R%2DHSA%2D211897
https://www.genome.jp/dbget-bin/www_bget?hsa00980
https://ctdbase.org/basicQuery.go?bqCat=go&bq=cytochrome+P450
https://ctdbase.org/basicQuery.go?bqCat=gene&bq=cytochrome+P450
Known effects of Endotoxin Cytokine Storm on P450
In 2012 an interesting paper showed that Interleukin 6, one of the major mediators of Endotoxin Toxicity impacts Cytochrome 450 pathways.3 Unfortunately it is behind a paywall, but the abstract is useful.
Read more about Interleukin 6 upregulation by the Endotoxin in the jabs.45
More on Cytokine Storm featuring the Interleukins here.6
Liver impacts should be the focus
Since much of the P450 activity occurs in the Liver, I will probably add to an earlier article.7
According to one reference the P450 Cytochrome superfamily is not found in E. coli.8
Looking forward to comments.
Pfizer BioNTech Covid19 Jab Multiple Trials Trail
As many authors have discussed the failure of the BioNTech Pfizer Covid19 jabs and the massive casualties, this post is a quick guide to the multiple Phase 1/2/3 trials they launched around the world involving tens of thousands of recruited volunteers.
Trifluoroacetate from Pfizer Nirmatrelvir
Pfizer say, since their jabs don’t work, take 2 pills to reduce your chances of Covid19 Death. They sell packages of pink and white pills to be taken together. 77.3% of those who take these pills suffer Adverse events.Geoff Pain PhD is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
Kim S, et al. 2012. Interleukin-6 and cytochrome-P450, reason for concern? https://link.springer.com/article/10.1007/s00296-012-2423-3
Extreme Toxicity of Endotoxins in Pfizer Jabs
How much Endotoxin is in the Pfizer Jabs? Perhaps we should ask Dr Jordon T Walker, Pfizer executive in charge of corporate strategy for expanding use of mRNA. See the 17 February 2023 update below. Despite US Court order, the document released by Pfizer on its jab testing with Rhesus Macaques using drug product made by BioNTech in Germany and imported to…
Epigenetics of Endotoxin Poisoning from Pfizer Jabs
In earlier articles I discussed the use of Escherichia coli Bacteria in production of the Pfizer jabs and how supertoxic Endotoxins carry through to the vials. Pfizer is legally obliged to measure and report the Endotoxin levels in the jabs but so far has redacted all documents that include actual measured levels using the Horseshoe Crab Blood test.
Pfizer jabs create the perfect Cytokine Storm
All Pfizer Jab Symptoms fit Endotoxin Damage I have been looking for a suitable illustration of the effects of the Pfizer jabs on the human body and suggested, during a video conference with my friends discussing the US Court ordered release of Pfizer trial and post-marketing experience Adverse Events, that someone with the necessary artistic skills coul…
Rapid Liver Failure after Pfizer jabs most likely due to miR-155 upregulation by Endotoxin
In a previous article I showed how Heart Damage caused by mRNA jabs can be explained by the catalytic effects of upregulation of the microRNA molecule known as miR-155. Liver Failure during the Trial Pfizer knew from its clinical trial and first 90 days of mass jabbing that severe and Fatal Liver Failure was a clear signal of systemic assault by its produ…
https://en.wikipedia.org/wiki/Cytochrome_P450
Great information and thanks for trying to make it understandable. Have other affects been noted in the pancreas? A friends son (35 yo) has just been diagnosed with insulin dependent diabetes (very fit/healthy otherwise) and spoken to paediatric diabetic nurse, who says they are much busier than normal. By the way, both of the aforementioned are totally vax believers.