Alzheimer's Disease caused by Jab Endotoxin
Endotoxin is present in all brands of Covid19 jabs and is known to upregulate microRNA miR-155-5p that enhances extracellular Aβ Aggregation
Endotoxin in jabs, especially the small, most toxic, Lipid A, travels immediately after jabbing to the Brain as discussed previously.1 2
There it initiates a number of destructive pathways3 and upregulates expression of numerous microRNAs, including miR-155 that I have shown causes Myocarditis4 and other diseases.
A 2023 review5 provides many useful references. Here is Figure 1 from Liu and coworkers.
I have slightly modified their Figure caption to explain some abbreviations.
miR-155 regulates the deposition of Aβ (extracellular amyloid-β) by inducing SKP2 (S-phase kinase-associated protein) or SNX27(Sorting Nexin). miR-155 might be involved in NFT (intracellular NeuroFibrillary Tangles) by regulating GSK3β (Glycogen Synthase Kinase-3), AMPK (Adenosine-Monophosphate activated Protein Kinase), PKI-α (Protein Kinase A Inhibitor), mTOR (Mammalian Target of Rapamycin), MAPK (Mitogen-Activated Protein Kinase), or Wnt (Wingless-related integration site) pathways, which evolves from assembled hyperphosphorylated tau protein and induces synaptic dysfunction. miR-155 was also involved in synaptic dysfunction by regulating c/EBPβ (Enhancer Binding Protein)/SNX27 signaling pathway. miR-155 can activate microglia via targeting SOCS-1(Suppressor Of Cytokine Signaling) or SHIP1(SH2 domain containing Inositol-5-Phosphatase). The activated microglia can phagocytize aggregated Aβ but also can release pro-inflammatory cytokine, which accelerates Aβ aggregation and leads to neuroinflammation. NLRP4 (Nucleotide-binding and Leucine-rich repeat Receptor Pyrin Domain Containing). IL (Interleukin). TNF (Tumor Necrosis Factor). IFN (Interferon)
Wang and coworkers demonstrated the importance of miR-155-5p by investigating the Nuclear Factor Kappa B (NF-κB) pathway and inhibitor of NF-κB kinase β (IKKβ) that are involved in Alzheimer disease (AD) pathogenesis.6
Can Endotoxin Induced Alzheimer’s be reversed?
A paper from 2018 discusses the role of Lipopolysaccharide Binding Protein countering Endotoxin.7
The authors concluded:
We therefore suggest that LBP might eventually be used as treatment to prevent the damaging effect of LPS on fibrin(ogen) and hypercoagulation, and even to prevent (at least in part) the deposition of amyloid-β (Aβ) plaques in the brain and the loss of cognitive function that accompanies this neurodegenerative disease. However, we note that a control protein, such as human IgG should, in future, be used to present the specific effect of LBP on amyloid formation, to further elucidate the physiological processes discussed in this paper. In future, our hypothesis could also be tested in a transgenic murine model of AD (TgAD) or the 5xFAD (amyloid over-producing) model or equivalent.
Fatigue, Headache, Muscle Pain, Fever and Chills after Pfizer Jabs match Endotoxin Effects
Billions have been told Jab Symptoms are “Normal” Start by looking at what happens when 1 nanogram/kg of Bacterial Endotoxin (LipoPolySaccharide, LPS) is injected intravenously, with some going into the Brain of a Human Volunteer. In this experiment, Positron Emission Tomography (PET) using radiotracer [
Parkinson's Disease after Pfizer jabs most likely due to Endotoxin in every vial
In a recent article I wrote about Endotoxin in Pfizer jabs being known to readily cross the Blood-Brain-Barrier and target Microglia, causing many of the common Adverse Events reported by hundreds of millions of Jabbees. Endotoxin also damages other types of Brain cells, including Astrocytes.
Epigenetics of Endotoxin Poisoning from Pfizer Jabs
In earlier articles I discussed the use of Escherichia coli Bacteria in production of the Pfizer jabs and how supertoxic Endotoxins carry through to the vials. Pfizer is legally obliged to measure and report the Endotoxin levels in the jabs but so far has redacted all documents that include actual measured levels using the Horseshoe Crab Blood test.
Pfizer Process 2 Endotoxin Myocarditis Death Toll - Dr Aseem Malhotra knows all about it
Jab pushers are outraged at the overwhelming success of the Australian lecture tour by British Cardiologist Dr Aseem Malhotra. So let’s look at Jab Deaths caused by the Heart condition known as Myocarditis. 139 Medically Confirmed Myocarditis Deaths
Liu JJ, et al. 2023. Pathogenesis of miR-155 on nonmodifiable and modifiable risk factors in Alzheimer’s disease. https://alzres.biomedcentral.com/articles/10.1186/s13195-023-01264-z
Wang W, et al. 2021. MicroRNA-155-5p Targets SKP2, Activates IKKβ, Increases Aβ Aggregation, and Aggravates a Mouse Alzheimer Disease Model. https://academic.oup.com/jnen/article/81/1/16/6448595
Etheresia Pretorius, Janette Bester, Martin J. Page and Douglas B. Kell. 2018. The Potential of LPS-Binding Protein to Reverse Amyloid Formation in Plasma Fibrin of Individuals With Alzheimer-Type Dementia. https://www.frontiersin.org/articles/10.3389/fnagi.2018.00257/full
Another brilliant post . I’ll have to print to study but your posts are sooo worth it . Thank you for your efforts .