PAIN from Covid19 Jabs caused by Endotoxin is amplified by Opioids
Oxycodone, Fentanyl, and Morphine amplify Endotoxin induced Pain
In earlier articles, I showed that the Pain experienced by Covid19 Jabbees is caused by Endotoxin.12 There I covered the role of Pain receptor TRPA1.
Pfizer reported 121 different types of Pain after its jabs in its PSUR3 to June 2022.
Prompted by my friend Rob, who suffers Chronic Pain, I looked at a recent media report3 of the escalating tragic deadly outcomes of Opioid drug use and that led to me finding some very useful research on Acute and Chronic Pain by researchers in Colorado and Texas.4
Allodynia from Endotoxin
Allodynia is Pain due to a stimulus that does not normally provoke pain.5
An example would be a light feather touch (that should only produce sensation), causing pain.
Fibromyalgia is just one cause of Allodynia.
Allodynia is exacerbated by Morphine which non-stereoselectively activates TLR4 and induces Proinflammatory Cytokines. This is the identical mechanism and receptor that causes Cytokine Storm in reaction to Endotoxin in jabs.6
Then I found an excellent paper by researchers Reeve and coworkers who showed that intrathecal injection of Picogram7 amounts of Endotoxin enhanced the activity of Dorsal Horn Neurons.8
In the same year, Wang and coworkers in Colorado and Adelaide9 performed detailed experiments to look at the Morphine interaction with Endotoxin receptor TLR4 and showed that Morphine binds to an accessory protein of Toll-like receptor 4 (TLR4), Myeloid Differentiation Protein 2 (MD-2), inducing TLR4 oligomerization and triggering Proinflammation with no involvement of opioid receptors.
Here is part of their Figure 2
The relevant part of the caption reads:
(C and D) Structural comparison of apo- and ligand-bound MD-2. The ligands are shown in a ball-and-stick presentation. X-ray crystal structure of apoMD-2 (cyan; PDB ID 2E56) superimposed with (C) X-ray crystal structure of the LPS-bound MD- 2 (pink; PDB ID 3FXI) or (D) morphine-bound MD-2 (yellow) derived from atomic molecular dynamics simulation.
Here LPS = Endotoxin. Residue F126 is located in the core of the (TLR4/MD-2)/(TLR4/MD-2) oligomerization interface and initiates structural changes in MD-2 upon LPS (Endotoxin) binding.
Pain from Covid19 Jabs is caused by Endotoxin
Pain receptor TRPA1 is the focus of this article. Lovely Figure showing its Pain centres from Silverman and coworkers.Geoff Pain PhD is a reader-supported publication. Please consider upgrading to paid subscriber. Other TRP channels are also responsive to Endotoxin
Fatigue, Headache, Muscle Pain, Fever and Chills after Pfizer Jabs match Endotoxin Effects
Billions have been told Jab Symptoms are “Normal” Start by looking at what happens when 1 nanogram/kg of Bacterial Endotoxin (LipoPolySaccharide, LPS) is injected intravenously, with some going into the Brain of a Human Volunteer. In this experiment, Positron Emission Tomography (PET) using radiotracer [
Chris McGreal. 28 Jan 2024. Opioids crisis ‘I don’t see how it ends’: expert sounds alarm on new wave of US opioids crisis. https://www.theguardian.com/us-news/2024/jan/28/us-opioids-crisis-fentanyl-appalachia
Suzanne M. Green-Fulgham, Jayson B. Ball, Andrew J. Kwilasz, Timothy Fabisiak, Steven F. Maier, Linda R. Watkins, and Peter M. Grace. 2019. Oxycodone, fentanyl, and morphine amplify established neuropathic pain in male rats. https://journals.lww.com/pain/abstract/2019/11000/oxycodone,_fentanyl,_and_morphine_amplify.22.aspx
Yusi He and Peggy Y. Kim. 2023. Allodynia Continuing Education Activity. https://www.ncbi.nlm.nih.gov/books/NBK537129/
Pfizer jabs create the perfect Cytokine Storm
All Pfizer Jab Symptoms fit Endotoxin Damage I have been looking for a suitable illustration of the effects of the Pfizer jabs on the human body and suggested, during a video conference with my friends discussing the US Court ordered release of Pfizer trial and post-marketing experience Adverse Events, that someone with the necessary artistic skills coul…
Graphene Oxide, Gold and Organometallic Ferrocene make sensitive Endotoxin Detector
In 1980 I had the pleasure of meeting Nobel Prize winner Professor Sir Geoffrey Wilkinson who made Ferrocene, a “sandwich molecule”, where two carbon pentagons bond to an Iron atom. Wilkinson was a supervisor of my PhD supervisor Ron Dickson. I had made Ferrocene as an undergraduate experiment and went on to make new similar molecules of the Platinum Gr…
Alison J. Reeve, Sadhana Patel, Alyson Fox, Katherine Walker, Laszlo Urban. 2012. Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat. https://onlinelibrary.wiley.com/doi/abs/10.1053/eujp.2000.0177
Xiaohui Wang, Lisa C. Loram, Khara Ramos, Armando J. de Jesus, Jacob Thomas, Kui Cheng, Anireddy Reddy, Andrew A. Somogyi, Mark R. Hutchinson, Linda R. Watkins, Hang Yin. 2012. Morphine activates neuroinflammation in a manner parallel to endotoxin. https://www.pnas.org/doi/full/10.1073/pnas.1200130109