Autoimmune Diseases caused by Endotoxin in mRNA Jabs include Myocarditis, Pericarditis, Lupus
mRNA jabs were designed to make Spike Protein invade your cells so they become targets for Destruction, but the Endotoxin in all vials does that faster.
Recently I briefly mentioned that Endotoxin, as found in every vial of Moderna and Pfizer jab, causes Autoimmune Diseases.1
While mRNA in the jabs2 undoubtedly was designed to make Spike Protein invade your cells so they become targets for Destruction, with the announced lie that would be confined to your Muscle Cells, we need to look in more detail at the Autoimmune effects of the E coli Endotoxin arising from production.
The Epigenetics of Endotoxin is the key.3
Endotoxin induces Cytokine Release Syndrome
Otherwise known as Cytokine Storm, or as I prefer to call it Cytokine Hurricane.
Acronyms are rife in the business of Toxicology of the jabs.
MIG stands for Monokine Induced by interferon (IFN)-γ (the G is for Gamma).
MIG and its receptor are known to cause Autoimmunity via a Positive Feedback Loop involving recruitment of Th1 lymphocytes which in turn stimulates MIG secretion from Thyrocytes4 and numerous other types of cells, creating an amplification of the Autoimmune process that destroys the organ.5
The reader is encouraged to examine a great collection of references to Thyroid damage by Covid19 and the jabs.6 One of these showed that the Pfizer jab causes destruction of the Thyroid gland within 2 days.7
E coli Endotoxin is a superior stimulator of MIG Autoimmune response than that derived from other types of bacteria.8
Endotoxin as a cause of Thyroid diseases via disruption of the Kynurenine pathways has been reviewed.9
This KEGG pathway shows how Endotoxin is involved in Thyroid Autoimmune Disease.10
Antiphospholid Antibodies
Autoimmune diseases are caused by development of Antiphospholid Antibodies.
Endotoxin Lipid A, as found in Pfizer jabs, has been shown in Rabbits to induce Antiphospholid Antibodies, specifically Systemic Lupus Erythematosus (SLE) type-aCL (β2GPI-dependent) and Lupus Anticoagulant.11
Repeated Influenza Jabs induce Autoimmune Diseases
It has been shown12 that repeated Influenza jabs increases risk of Autoimmune Systemic Lupus Erythematosus (SLE), Multiple Sclerosis, Guillain-Barré syndrome.
Myelin-Associated Glycoprotein (MAG) antibodies attack the system.
It is known that broadly reactive Influenza Antibodies also bind other proteins including Insulin, Endotoxin (LipoPolySaccharide, LPS), and double-stranded DNA (dsDNA), demonstrating a propensity for autoreactivity.
Labombarde et al. pointed out that the increased levels of broadly reactive antibodies may be the result of non-specific Inflammation that promotes the expansion of anti-MAG and -ganglioside antibodies that do not bind influenza antigens.
Pfizer reports of Autoimmune Disease
Previously I wrote that, to 15 April 2022, Pfizer reported 1,461 cases of Guillain-Barré Syndrome (GBS) and showed how that can be related to Endotoxin in the jab.13
Endotoxins from gram-negative E coli Bacteria, as used in Pfizer jab production, cause paralysis via molecular mimicry between bacterial glycoconjugates and peripheral nerve gangliosides.14
Pfizer listed numerous Autoimmune Diseases as Adverse Events after its jabs under various headings, including these examples of case numbers to April 2022:
Myocarditis 11,299, Autoimmune Myocarditis 4
Pericarditis 9,186 - Read more about CD4/CD8 ratios.15
Eczema 2,484, Dyshidrotic Eczema 102
Thrombocytopenia 1,907, Immune thrombocytopenia 835, Thrombosis with thrombocytopenia syndrome 79
Rheumatoid Arthritis 1,356, Rheumatic disorder 425,
Psoriasis 1,235, Guttate Psoriasis 74, Pustular psoriasis 30, Erythrodermic Psoriasis 14, Nail psoriasis 9, Rebound Psoriasis 3
Polymyalgia Rheumatica 853
Fibromyalgia 673
Multiple Sclerosis 517, Multiple sclerosis relapse 435, Relapsing-remitting Multiple Sclerosis 16, Relapsing Multiple Sclerosis 9, Multiple sclerosis pseudo relapse 7
Myositis 515
Autoimmune disorder 496
Diabetes mellitus 413, Diabetes mellitus inadequate control 217, Type 1 Diabetes mellitus 202, Type 2 Diabetes mellitus 98, Diabetes insipidus 24, Gestational diabetes 19, Latent Autoimmune Diabetes in adults 8, Fulminant type 1 diabetes mellitus 5, Insulin resistant diabetes 2, Insulin-requiring type 2 diabetes mellitus 1
Crohn’s disease 342
Systemic Lupus Erythematosus 296, Cutaneous Lupus Erythematosus 24, Lupus-like syndrome 22, Systemic Lupus Erythematosus rash 17, Lupus nephritis 13, Chronic Cutaneous Lupus Erythematosus 8, Subacute Cutaneous Lupus 8, Acute Cutaneous Lupus Erythematosus 6
Autoimmune Thyroiditis 273, Thyroiditis subacute 263, Thyroiditis 205, Thyroiditis acute 52, Autoimmune Thyroid disorder 12, Autoimmune Hypothyroidism 8
Rhabdomyolysis 271
Giant Cell Arteritis 235
Ankylosing Spondylitis 193, Joint Ankylosis 58
Henoch-Schonlein purpura 147, Henoch-Schonlein purpura nephritis 3
Autoimmune Haemolytic Anaemia 123, Autoimmune anaemia 8
Autoimmune Hepatitis 151
Multisystem Inflammatory Syndrome in children 67, Multisystem Inflammatory Syndrome 42, Multisystem Inflammatory Syndrome in Adults 16
Encephalitis Autoimmune 58, Autoimmune encephalopathy 5
Autoimmune Myositis 34, Immune-mediated Myositis 7, Necrotising Myositis 6, Orbital Myositis 5
Autoimmune Arthritis 23, SLE arthritis 6
Autoimmune Pancreatitis 15
Autoimmune Neuropathy 14
Autoimmune Neutropenia 9
Autoimmune Colitis 6, Autoimmune enteropathy 1
Autoimmune Demyelinating Disease 6
Autoimmune Uveitis 6
Autoimmune Dermatitis 5, Autoimmune Blistering disease 4
Autoimmune Eye disorder 3
Autoimmune Lung disease 3
Autoimmune Lymphoproliferative syndrome 3
Autoimmune Inner Ear disease 2
Autoimmune Cholangitis 2
Autoimmune Nephritis 1
Autoimmune Pancytopenia 1
Polyglandular Autoimmune syndrome 2
Note these include medical specialist diagnoses using specific disease names, which helps to dilute the clear warning signal. Pfizer has of course no interest in consolidating this tragic list of suffering.
Interleukin 6 from the jabs causes Autoimmunity
A key paper by Toshio Hirano covers his work in the identification and isolation of Interleukin 6 (IL-6) and its role in Autoimmune diseases, including Arthritis.16
Th17 helper cells, an arm of the CD4+ T cell effector response, secrete several proinflammatory cytokines, such as IL-17, and induce various chronic inflammatory conditions, including autoimmune diseases. IL-6–mediated signaling via STAT3 increases the number of Th17 cells by enhancing RORγ expression. Here we see Hirano’s scheme of IL6 pathways leading to Autoimmunity, including Rheumatoid Arthritis.
Hirano demonstrated Catalytic Positive Feedback Loop to non-immune cells in Autoimmune disease involving NFκB and STAT3 (JAK–Signal Transducer and Activator of Transcription 3).
The KEGG Pathway for Th17 Autoimmune Disease gives a simplified scheme.17
Interleukin 1 from the jabs causes Autoimmunity
As I recently highlighted, Endotoxin stimulates formation of numerous Interleukin molecules . In the case of IL-1β, which catalyzes expression of itself by initiating a Positive Feedback Loop, direct attack on multiple organs including the Heart is observed.1819
Multiple Sclerosis from Pfizer Jabs
A paper from Saudi Arabia alerted the world to MS case reports after jabbing.20
See a nice update from Steve Kirsch on the Multiple Sclerosis cases caused by the mRNA jabs.21 He included useful references.2223
Autoimmune Encephalomyelitis
Endotoxin is involved in reduction of Pro-antioxidant Transcription Factor Nrf2.24
Disruption of Nrf2 resulted in a more severe clinical course, a more rapid onset, and a greater percentage of mice with the disease. Furthermore, increased immune cell infiltration and glial cell activation in spine was observed. In conjunction, we observed increased inflammatory enzyme (iNOS, phox-47, gp91-phox, and phox-67), cytokine (IFN-gamma, IL1-b, TNF-alpha, and IL-12), and chemokine (BLC and MIG) gene expression levels in the Nrf2-deficient mice compared to the WT mice, supporting the notion that Nrf2 can modulate an autoimmune neuroinflammatory response. Our results show that the absence of Nrf2 exacerbates the development of EAE and thus suggests that activation of Nrf2 may then attenuate pathogenesis of autoimmune diseases such as MS as well as other neurodegenerative diseases that present with neuroinflammation.
Endotoxin inhibits glutathione synthesis by attenuating sumoylation of Nrf2 and the heterodimerization partner MafG (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G).25
More on Diabetes
See the nice article Stephanie Brail, with links to some peer-reviewed Case Studies and revelations of organizations claiming concern for Diabetes sufferers while actively promoting the jabs.26
September 2024 Update
Our friend Dr John B on X kindly drew our attention to an important review on Rheumatic Diseases associated with numerous types of Jabs over the years.27
"The disproportionality signal for rheumatic diseases was most pronounced in - HBV vaccines (ROR, 4.11; IC025, 1.90), - followed by COVID-19 mRNA (ROR, 2.79; IC025, 1.25), - anthrax (ROR, 2.52; IC025, 0.76), - papillomavirus (ROR, 2.16; IC025, 0.95), - encephalitis (ROR, 2.01; IC025, 0.58), - typhoid (ROR, 1.91; IC025, 0.44), - influenza (ROR, 1.49; IC025, 0.46), - and HAV vaccines (ROR, 1.41; IC025, 0.20)."
Unfortunately it is behind a paywall, but clearly shows mRNA Jabs are not alone in causing this Autoimmune suffering.
July 2026 Update
Our friend Bine Stebel discusses28 a 2009 free downloadble paper from Japan showing how Endotoxin induces Autommune Diseases where the researchers used GMO Mice.29
Abstract
Background
The cause of autoimmunity, which is unknown, is investigated from a different angle, i.e., the defect in immune ‘system’, to explain the cause of autoimmunity.
Methodology/Principal Findings
Repeated immunization with antigen causes systemic autoimmunity in mice otherwise not prone to spontaneous autoimmune diseases.
Overstimulation of CD4+ T cells led to the development of autoantibody-inducing CD4+ T (aiCD4+ T) cell which had undergone T cell receptor (TCR) revision and was capable of inducing autoantibodies.
The aiCD4+ T cell was induced by de novo TCR revision but not by cross-reaction, and subsequently overstimulated CD8+ T cells, driving them to become antigen-specific Cytotoxic T Lymphocytes (CTL).
These CTLs could be further matured by antigen cross-presentation, after which they caused autoimmune tissue injury akin to Systemic Lupus Erythematosus (SLE).
Conclusions/Significance
Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host’s immune ‘system’ by repeated immunization with antigen, to the levels that surpass system’s self-organized criticality.
Read more about the dangers of Endotoxin altering your CD4/CD8 Cell ratios.30313233
Bine also mentions a 2026 paper from Italy by Bellavite et al. who discuss Covid19 Jab induced Autoimmunity.34
That paper is useful because it mentions Covid19 Jab induced Leaky Gut,35 measurement with Zonulin36 and the importance of Lipopolysaccharide Binding Protein.37
Women suffer more from Pfizer Endotoxin
In 2014 Ugur Sahin and Özlem Türeci, co-founders of BioNTech, along with their colleague Katalin Karikó, mentioned the problem of Endotoxin as a contaminant in their planned mRNA jabs. In this article I will focus on the disastrous effects that the Pfizer BioNTech jabs have on females of all ages and explore the role of the toxic Endotoxin contaminant.
Robert W. Chandler and Amy Kelly. 2023. Report 70: Histopathology Series Part 4c – Autoimmunity: A Principal Pathological Mechanism of COVD-19 Gene Therapy Harm (CoVax Diseases) and a Central Flaw in the LNP/mRNA Platform. https://dailyclout.io/report-70-part-4c-clinical-evidence-supporting-the-hypothesis-that-autoimmunity-is-one-of-the-principal-pathological-mechanisms-of-harm-from-covid-19-gene-therapy-drugs/
Epigenetics of Endotoxin Poisoning from Pfizer Jabs
In earlier articles I discussed the use of Escherichia coli Bacteria in production of the Pfizer jabs and how supertoxic Endotoxins carry through to the vials. Pfizer is legally obliged to measure and report the Endotoxin levels in the jabs but so far has redacted all documents that include actual measured levels using the Horseshoe Crab Blood test.
Pezzano M. 2019. MIG in autoimmune thyroiditis: review of the literature Clin Ter. 170(4):e295-e300. doi: 10.7417/CT.2019.2151 https://pubmed.ncbi.nlm.nih.gov/31304519/
Fanny N Lauw, Andrew J H Simpson, Jan M Prins, Sander J H van Deventer, Wipada Chaowagul, Nicholas J White, Tom van der Poll. 2000. The CXC Chemokines Gamma Interferon (IFN-γ)-Inducible Protein 10 and Monokine Induced by IFN-γ Are Released during Severe Melioidosis. Infection and Immunity 68(7):3888–3893. https://journals.asm.org/doi/10.1128/iai.68.7.3888-3893.2000
Thyroid/Covid News Updates. https://poisonfluoride.com/phpBB3/viewtopic.php?f=66&t=2040
Kenya Ie, Kosuke Ishizuka, Tsubasa Sakai, Iori Motohashi, Shiko Asai, Chiaki Okuse. January 2023. Subacute Thyroiditis Developing Within 2 Days of Vaccination Against COVID-19 with BNT162b2 mRNA. European Journal of Case Reports in Internal Medicine. DOI: 10.12890/2023_003735. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930880/
Motohiro Matsuura, Kazuyoshi Kawahara, Takayuki Ezaki, Masayasu Nakano. 1996. Biological activities of lipopolysaccharide of Burkholderia (Pseudomonas) pseudomallei FEMS Microbiology Letters 137:79-83. https://academic.oup.com/femsle/article/137/1/79/459237
Krupa A and Kowalska I. 2021. The Kynurenine Pathway - New Linkage between Innate and Adaptive Immunity in Autoimmune Endocrinopathies. https://www.mdpi.com/1422-0067/22/18/9879
https://www.genome.jp/pathway/hsa05320
M Gotoh and J Matsuda. December 2016. Induction of anticardiolipin antibody and/or lupus anticoagulant in rabbits by immunization with lipoteichoic acid, lipopolysaccharide and lipid A. Lupus. 5(6):593-7. doi: 10.1177/096120339600500606. https://journals.sagepub.com/doi/abs/10.1177/096120339600500606
Labombarde JC, et al. 2022. Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity. https://www.cell.com/cell-reports/fulltext/S2211-1247(22)00215-7
Guillain-Barré Syndrome expected from Pfizer Endotoxins
Facial and peripheral paralysis were recognized early as Neurological Adverse Reactions after Pfizer jabbing trials. These were included among Neurological Adverse Events of Special Interest (AESIs including Demyelination, i.e. destruction of the protective sheath on our Nerves).
C. W. Ang, J. D. Laman, H. J. Willison, E. R. Wagner, H. P. Endtz, M. A. De Klerk, A. P. Tio-Gillen, N. Van den Braak, B. C. Jacobs, and P. A. Van Doorn. March 2002. Structure of Campylobacter jejuni Lipopolysaccharides Determines Antiganglioside Specificity and Clinical Features of Guillain-Barré and Miller Fisher Patients. Infection and Immunity. 70(3):1202-1208. https://journals.asm.org/doi/10.1128/IAI.70.3.1202-1208.2002
Pericarditis Deaths after Covid19 Jabs
Mass marketing profiteers downplay agonizing Chest Pain after jabs, telling the victims the Heart will heal itself.
Hirano T. 2010. Interleukin 6 in autoimmune and inflammatory diseases: a personal memoir. https://www.jstage.jst.go.jp/article/pjab/86/7/86_7_717/_article
https://www.genome.jp/pathway/hsa04657
Endotoxin in Pfizer Jabs causes Heart Damage
As I have recently stressed, every vial of Pfizer jab contains Endotoxin arising from the manufacturing process. The jabs are known to cause Heart Damage, evident from the initial trial.Geoff Pain PhD is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
Yishay Szekely, Yaron Arbel. June 2018. A Review of Interleukin-1 in Heart Disease: Where Do We Stand Today? Cardiology and Therapy. 7(1):25-44. doi: 10.1007/s40119-018-0104-3. https://link.springer.com/article/10.1007/s40119-018-0104-3
Majed Alluqmani. March 2023. New Onset Multiple Sclerosis Post-COVID-19 Vaccination and Correlation With Possible Predictors in a Case-Control Study. Cureus 15(3):e36323. https://www.cureus.com/articles/137279-new-onset-multiple-sclerosis-post-covid-19-vaccination-and-correlation-with-possible-predictors-in-a-case-control-study#!/
Ariana R Tagliaferri, George Horani, Katherine Stephens, Patrick Michael. November 2021. A rare presentation of undiagnosed multiple sclerosis after the COVID-19 vaccine. J Community Hosp Intern Med Perspect. 11(6):772-775. https://www.tandfonline.com/doi/full/10.1080/20009666.2021.1979745
Joachim Havla, Yannick Schultz, Hanna Zimmermann, Reinhard Hohlfeld, Adrian Danek, Tania Kümpfel. 2022. First manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine. https://link.springer.com/article/10.1007/s00415-021-10648-w
Delinda A. Johnson, Sara Amirahmadi, Charlotte Ward, Zsuszanna Fabry, and Jeffrey A. Johnson. 2010. The Absence of the Pro-antioxidant Transcription Factor Nrf2 Exacerbates Experimental Autoimmune Encephalomyelitis. TOXICOLOGICAL SCIENCES 114(2):237–246. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902921/
Tomasi ML. 2014. Molecular Mechanisms of Lipopolysaccharide-mediated Inhibition of Glutathione Synthesis in Mice. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943979/
Jiyeon Oh, Hyesu Jo, Jaeyu Park, Hayeon Lee, Hyeon Jin Kim, Hyeri Lee, Jiseung Kang, Jiyoung Hwang, Selin Woo, Yejun Son, Soeun Kim, Lee Smith, Masoud Rahmati, Louis Jacob, Jinseok Lee, Jun Hyuk Lee, Guillermo F. López Sánchez, Elena Dragioti, Raphael Udeh, Nicola Veronese, Pinar Soysal, Ho Geol Woo, Dong Keon Yon. 2024. Global burden of vaccine-associated rheumatic diseases and their related vaccines, 1967–2023: A comprehensive analysis of the international pharmacovigilance database. https://onlinelibrary.wiley.com/doi/abs/10.1111/1756-185X.15294
Ken Tsumiyama, Yumi Miyazaki, Shunichi Shiozawa. 2009. Self-Organized Criticality Theory of Autoimmunity. PlosOne. 4(12): e8382. doi:10.1371/journal.pone.0008382 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008382
CD4/CD8 Ratio is altered by Endotoxin in Covid19 Jabs
I discussed the CD4/CD8 ratio in an earlier post this year.
Endotoxin replacing PEG in Lipid Nanoparticles increases CD8 T Killer cells
In 2016 researchers at Harvard designed Lipid Nanoparticles with a slightly negative Zeta potential to transfect dendritic cells, macrophages, and neutrophils, which we know are the primary targets of the mRNA jabs.
Glioblastoma Lethality predicted by CD68 adds to Endotoxin link - RIP Australian Oncologist Richard Scolyer who died "having a crack" at finding a cure
ABC TV 7.30 senior reporter Fiona Willan and anchor Sarah Ferguson produced this video aired on 8 June 2026.
QoVax Testing - What were they looking for when anticipating Jab Harms ?
QoVax was designed to look for genetic, including racial, variation in response to multiple Covid19 Jabbing.
Paolo Bellavite, Giuseppe Di Fede, Mauro Mantovani and Elisabetta Zanolin. 2026. Autoimmune Features of Post-COVID-19 Vaccination Syndrome and Their Impacts on the Renin–Angiotensin System. Vaccines. 14:354. https://doi.org/10.3390/vaccines14040354.
Leaky Gut caused by Endotoxin in Jabs
Jab in the Arm, opens your Gut and lets Toxins invade your system.
Endotoxin Binding Protein as a Prognostic marker of Death and Disease
I have mentioned Lipopolysaccharide Binding Protein (LPB) in various articles but think we should change its name to align with the Therapeutic Goods Administration and all jab regulatory bodies around the world who report that they have conducted Endotoxin tests on all released batches or accepted certificates from other countries accredited testing la…
























Sorry mate, did the redaction of Endotoxin get reversed? If not will this be in the last lot of Pfizer docs to be court ordered released?
I'm guessing the autoimmune myocarditis had lymphocytes through the tissue? This would mean deaths/autopsy?
Does this mean that any number of the other cases may be non fatal and unable to label autoimmune related?