Remdesivir Deaths - was Endotoxin a factor?
When I first saw the chemical structure of Remdesivir I worried about the organophosphate and cyanide groups. Looking at symptoms, I think Endotoxin contamination as found in India, caused Deaths
In 2017 Ralph Baric published his work on extending the Ebola Virus proposed treatment Gilead drug named GS-5734, later named Remdesivir to Coronaviruses.1
Baric, as most people know, is famous for making and genetically modifying Viruses as part of the US Bioweapon industry that creates marketing opportunities for Jab and Pill merchants.
Here is part of his Figure 3 in Sheahan et al.
GS-5734 is effective against a diverse array of human and zoonotic CoV in HAE.
(A) Neighbor-joining trees created with representatives from all four CoV genogroups showing the genetic similarity of CoV nsp12 (RdRp) and CoV spike glycoprotein, which mediates host tropism and entry into cells.
Text color of the virus strain label corresponds to virus host species on the left.
The heatmap adjacent to each neighbor-joining tree depicts percent amino acid identity (% A.A. identity) against SARS-CoV or MERS-CoV.
In the body of the paper you can find interesting details:
Viruses
SARS-CoV expressing GFP (GFP replaces ORF7) and MERS-CoV expressing RFP (RFP replaces ORF3) were created from molecular complementary DNA clones as described (11, 20).
To create SARS-CoV and MERS-CoV expressing nLUC, the genes for GFP and RFP were replaced with nLUC and isolated as referenced above. Recombinant human CoV NL63 and recombinant Bat CoV for strains HKU3, HKU5, WIV1, and SHC014 were created as described (5, 6, 12, 16, 17).
And at the end:
Competing interests: The authors affiliated with Gilead Sciences are employees of the company and may own company stock. M.O.C., J.Y.F., R.J., R.L.M., A.S.R., and D.S. are listed as inventors on international application no. PCT/US2016/ 052092 filed by Gilead Sciences Inc., directed to methods of treating Coronaviridae virus infections.
The patent application was expanded for world coverage and has now ceased after patents were granted in a number of countries.2 It covered Arenaviridae3 as well as Coronaviridae.4
The Gilead application and the Sheahan/Baric paper both cite the 2016 paper reporting on use of Remdesivir in Ebola by the US Bioweapons developers at Frederick Maryland, Gilead Sciences, CDC in Georgia and Boston University School of Medicine.5
In 2024 US Bioweapons developers and Gilead reported further work on Remdesivir for Ebola.6 This time United States Army Medical Research Institute of Infectious Diseases, Frederick Maryland collaborated with Geneva Foundation Washington, PharPoint Research, Inc. North Carolina, Labcorp Early Development Laboratories Wisconsin, and Gilead Sciences Calfornia. Interestingly, some of the authors inducated they had moved on to other employers including BioMérieux Utah, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring Maryland and Tonix Pharmaceuticals Frederick, Maryland.
Readers are encouraged to tell us what they know about ownership and other activites of companies mentioned.
Deaths Update 26 August 2025
Now that the FAERS database is updated in near real time, you can check whenever you like.
Today the US FAERS database showed 2,719 Deaths and 8,605 Serious cases from a total of 10,533 Adverse Event Reports for Remdesivir.
For tradename Veklury US FAERS database showed 746 Deaths and 2,315 Serious cases from a total of 2,718 Adverse Event Reports.
When first posted this article, the US FAERS database showed 2,480 Deaths and 7,834 Serious cases from a total of 9,696 Adverse Event Reports for Remdesivir, Gilead tradename Veklury. This is likely to be a gross underestimate of harm.
VigiAccess Database Remdesivir Deaths
On 13 September 2021 Dr Tess Lawrie accessed the Vigiaccess database7 of the WHO and produced a Table comparing the number of Deaths and Adverse Drug Reaction Reports (ADRs) for Ivermectin, all Covid19 Jabs and Remdesvir to that date.
Note 557 Deaths recorded after taking Remdesivir from a total of 7,262 ADRs, making it far more toxic than the Covid19 jabs and Ivermectin.
Some prominent researchers from US, Israel, Norway and Australia made a submission to the US FDA including this Table.8
On 24 March 2024, the number of reports at VigiAccess for Remdesivir was 11,215.
How many Deaths now? I could not see the data for that.
In Australia the Therapeutic Goods Administration (TGA) reports 14 Deaths after taking this drug.
Here is its molecular structure. In the body it is rapidly converted to other molecules.
Read about the different optical isomers of Remdesivir.9
Paul Elias Alexander promoted Remdesivir
The Wellness Company executive Paul Elias Alexander, when working for the World Health Organization (WHO) and the Pan American Health Organization in Washington DC, published a paper in May 2020 that served to promote the use of Remdesivir. It was simply a review of 2 clinical trials that claimed a reduction in time to recovery and reduced risk of Serious Adverse Events.10
Many will recall Anthony Fauci made a video using exactly these claims in the presence of President Donald Trump. See the collection of videos presented by James Roguski.11
On the strength of this Trump was given a cocktail of drugs, including Remdesivir.12
Some more interesting history can be found in the article by Brucha Weisberger.13
Richard M Fleming conducted a clinical trial involving numerous drugs in which 1 patient given Remdesivir died.14
TGA allows dodgy imports of Remdesivir
TGA allowed import of Remdesivir in September 2021, Batch Number 21090201M (28,000 units) despite the fact that it did not conform to the requirements of Therapeutic Goods Order No. 91 - Standard for labels of prescription and related medicines (TGO 91).15
TGA did the same again in February 2022.16
Remdesivir Mode of Action
The Product information states:
Remdesivir is an Adenosine analogue nucleotide prodrug that distributes into cells where it is metabolised to form the pharmacologically active nucleoside triphosphate metabolite.
Remdesivir is a substrate for Esterases in plasma and tissue and drug metabolising enzyme CYP3A4 and is a substrate for Organic Anion Transporting Polypeptides 1B1 (OATP1B1) and P-glycoprotein (P-gp) transporters.
In vitro, Remdesivir is an inhibitor of CYP3A4, UGT1A1, UGT1A3, UGT1A4, OATP1B1, OATP1B3, OAT3, OCT1, MRP4 and MATE1.
Remdesivir Adverse Events and Deaths
I previously mentioned that Remdesivir causes reactivation17 of Kaposi’s sarcoma-associated herpesvirus (KSHV), Shingles and Epstein-Barr Viruses via the MAPK pathway and further promote virion replication via NF-κb signaling, which is known to be the result of Endotoxin poisoning.18
Other symptoms reported for Remdesivir victims include:
Abdominal pain
Alanine Aminotransferase increased
Alkaline Phosphatase increased
Anaphylaxis, Hypersensitivity
Angioedema
Aspartate Aminotransferase increased
Asthma
Bradycardia
Bronchospasm
Cardiac failure
Conjugated Bilirubin increased
Diaphoresis
Dyspnea
Fever
Headache
Hepatic, Liver Failure
Hyperhidrosis
Hypertension
Hypotension
Hypoxia
Liver inflammation
Loss of consciousness
Multiple organ dysfunction syndrome
Myocarditis
Nausea
Palmar erythema
Presyncope
Prothrombin time increased
Rash
Respiratory failure
Severe Renal (Kidney) Toxicity as observed in monkeys and rats
Shivering
Tachycardia
Tendon disorder
Tinnitus
Vomiting
Wheezing
All of these are known effects of Endotoxin.19
Bradycardia most common in the Remdesivir Dead
5 of 14 Deaths reported to TGA DAEN involved Bradycardia.
Endotoxin is well known to induce Bradycardia when injected into Human Volunteers.20
Sulfobutyl Betadex Sodium
Remdesivir contains the Sodium salt of the a polyanionic cyclic oligosaccharide Sulfobutyl ether β-cyclodextrin, also known as Sulfobutyl Betadex Sodium.
This is known to accumulate in patients with decreased renal function.
How much Endotoxin is in Remdesivir ?
In Australia all injectable drugs are supposed to be tested for Endotoxin.
We know2122 that Gilead tests for Endotoxin in Remdesivir, but so far I have not found any reported levels.
In 2021 in India, Endotoxin contamination was identified as a major hazard leading to a Recall of Batch V100167. Batch V100156 was also causing severe reactions.2324
23 July 2024 Update
See more interesting history.25
January 2025 Update
See the tragedy of EUA for Children posted by Lawyer Lisa.26
At FAERS, to 31 December 2024, for Remdesivir there were recorded 2,624 Deaths, 8,376 Serious Adverse Reaction reports from a total of 10,298 case reports.
March 2025 Update
For an excellent discussion of the first US Wuhan Covid19 case known to have been given Remdesivir who arrived on a direct flight in Seattle, see Deepak Natarajan.27
Compare with the first Wuhan Covid19 case confirmed in Melbourne.28
February 2026 Update
On 11 February 2026 the Mayo Clinic confirmed that Remdesivir is still being prescribed in the US.29
US FAERS now has 2,742 Deaths from 10,625 case reports, for generic Remdesivir, or a Death to Report Ratio of 25.8%.
US FAERS now has 752 Deaths from 2,756 case reports, for brand name Veklury, or a Death to Report Ratio of 27.3%.
Can you help find Remdesivir Endotoxin measurements?
Timothy P Sheahan, Amy C Sims, Rachel L Graham, Vineet D Menachery, Lisa E Gralinski, James B Case, Sarah R Leist, Krzysztof Pyrc, Joy Y Feng, Iva Trantcheva, Roy Bannister, Yeojin Park, Darius Babusis, Michael O Clarke, Richard L Mackman, Jamie E Spahn, Christopher A Palmiotti, Dustin Siegel, Adrian S Ray, Tomas Cihlar, Robert Jordan, Mark R Denison, Ralph S Baric. June 2017. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci Transl Med. 9(396):eaal3653. doi: 10.1126/scitranslmed.aal3653. https://www.science.org/doi/10.1126/scitranslmed.aal3653
WO2017049060A1. Inventor Michael O’ Neil Hanrahan Clarke, Joy Yang Feng, Robert Jordan, Richard L. Mackman, Adrian S. Ray, Dustin Siegel. Current Assignee. Gilead Sciences Inc. Methods for treating arenaviridae and coronaviridae virus infections. https://patents.google.com/patent/WO2017049060A1/en
https://en.wikipedia.org/wiki/Arenavirus
https://en.wikipedia.org/wiki/Coronaviridae
Travis K Warren, Robert Jordan, Michael K Lo, Adrian S Ray, Richard L Mackman, Veronica Soloveva, Dustin Siegel, Michel Perron, Roy Bannister, Hon C Hui, Nate Larson, Robert Strickley, Jay Wells, Kelly S Stuthman, Sean A Van Tongeren, Nicole L Garza, Ginger Donnelly, Amy C Shurtleff, Cary J Retterer, Dima Gharaibeh, Rouzbeh Zamani, Tara Kenny, Brett P Eaton, Elizabeth Grimes, Lisa S Welch, Laura Gomba, Catherine L Wilhelmsen, Donald K Nichols, Jonathan E Nuss, Elyse R Nagle, Jeffrey R Kugelman, Gustavo Palacios, Edward Doerffler, Sean Neville, Ernest Carra, Michael O Clarke, Lijun Zhang, Willard Lew, Bruce Ross, Queenie Wang, Kwon Chun, Lydia Wolfe, Darius Babusis, Yeojin Park, Kirsten M Stray, Iva Trancheva, Joy Y Feng, Ona Barauskas, Yili Xu, Pamela Wong, Molly R Braun, Mike Flint, Laura K McMullan, Shan-Shan Chen, Rachel Fearns, Swami Swaminathan, Douglas L Mayers, Christina F Spiropoulou, William A Lee, Stuart T Nichol, Tomas Cihlar, Sina Bavari. March 2016. Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Nature. 531(7594):381-5. doi: 10.1038/nature17180. https://www.nature.com/articles/nature17180
Elizabeth E Zumbrun, Carly B Garvey, Jay B Wells, Ginger C Lynn, Sean A Van Tongeren, Jesse T Steffens, Kelly S Wetzel, Darrell L Wetzel, Heather L Esham, Nicole L Garza, Eric D Lee, Jennifer L Scruggs, Franco D Rossi, Elizabeth S Brown, Jessica M Weidner, Laura M Gomba, Kristan A O’Brien, Alexandra N Jay, Xiankun Zeng, Kristen S Akers, Paul A Kallgren, Ethan Englund, J Matthew Meinig, Jeffrey R Kugelman, Joshua L Moore, Holly A Bloomfield, Sarah L Norris, Tameka Bryan, Christie H Scheuerell, Jesse Walters, Nevena Mollova, Christiana Blair, Darius Babusis, Tomas Cihlar, Danielle P Porter, Bali Singh, Charlotte Hedskog, Sina Bavari, Travis K Warren, Roy Bannister. December 2024. A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques. Viruses. 16(12):1934. doi: 10.3390/v16121934. https://www.mdpi.com/1999-4915/16/12/1934
https://www.vigiaccess.org/
David Wiseman, Joshua Guetzkow, Hervé Seligmann and Samir Saidi. Docket No. FDA-2021-N-0965. Written comments submitted to: Vaccines and Related Biological Products Advisory Committee (VRBPAC) September 17, 2021 Meeting.
Andrew N Bigley, Tamari Narindoshvili, Frank M Raushel. 2020. A Chemo-Enzymatic Synthesis of the (RP)-Isomer of the Antiviral Prodrug Remdesivir. Biochemistry. 2020 Aug 10;59(33):3038–3043. https://pubs.acs.org/doi/10.1021/acs.biochem.0c00591
Paul Elias Alexander, Joshua Piticaru, Kimberley Lewis, Komal Aryal, Priya Thomas, Wojciech Szczeklik, Jakub Fronczek, Kamil Polok, Waleed Alhazzani and Manoj Mammen. 2020. Remdesivir use in patients with coronavirus COVID-19 disease: a systematic review and meta-analysis of the Chinese Lancet trial with the NIH trial. https://www.medrxiv.org/content/10.1101/2020.05.23.20110932v1
Jon Cohen. 2020. Update: Here's what is known about Trump's COVID-19 treatment. https://www.science.org/content/article/heres-what-known-about-president-donald-trump-s-covid-19-treatment
Richard M Fleming and Matthew R Fleming. 8 February 2021. FMTVDM Quantitative Nuclear Imaging finds Three Treatments for SARS-CoV-2. https://biomedres.us/fulltexts/BJSTR.MS.ID.005443.php
https://www.tga.gov.au/resources/section-14-consents/veklury-remdesivir-100-mg-powder-injection-vial-gilead-sciences-pty-ltd-con-864
https://www.tga.gov.au/resources/section-14-consents/veklury-remdesivir-100-mg-powder-injection-vial-gilead-sciences-pty-ltd-con-907
Shingles caused by Pfizer Jabs - Endotoxin or Spike?
In August 2021, Queensland Health decided to tell us all about Shingles with pictures. They used the occasion to promote Zostavax® vaccine which “is available on prescription to people aged 50 to 69 years and from 80 years, but it must be paid for by the patient.”
Epigenetics of Endotoxin Poisoning from Pfizer Jabs
In earlier articles I discussed the use of Escherichia coli Bacteria in production of the Pfizer jabs and how supertoxic Endotoxins carry through to the vials. Pfizer is legally obliged to measure and report the Endotoxin levels in the jabs but so far has redacted all documents that include actual measured levels using the Horseshoe Crab Blood test.
Endotoxin Harms List A-K
Alphabetical List based on the US Government Comparative Toxicogenomics Database after culling duplicates. Capital letters have no special significance. Endotoxin is present in all Covid19 Jab Brands. Soon we will learn how much. How might you use this list?
Lucas T. G. J. van Eijk, Peter Pickkers, Paul Smits, Martijn P. W. J. M. Bouw and Johannes G. van der Hoeven. 2004. Severe vagal response after endotoxin administration in humans. https://link.springer.com/article/10.1007/s00134-004-2477-0
European Medicines Agency. 3 April 2020. Summary on compassionate use.
Remdesivir Gilead International Non-proprietary Name: Remdesivir Procedure No. EMEA/H/K/005622/CU
Ahmed H. Bakheit, Hany Darwish, Ibrahim A. Darwish, and Ahmed I. Al-Ghusn. 2023. Remdesivir. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910426/
Priyanka Pulla. 23 Dec 2021. The dangerous failure to stop tainted remdesivir. https://www.livemint.com/science/health/the-dangerous-failure-to-stop-tainted-remdesivir-11640197634967.html
Priyanka Pulla. 6 Jan 2022. The Zydus Cadila Remdesivir Fiasco Wasn’t an Isolated Incident. https://science.thewire.in/health/cadila-remdesivir-endotoxins-hetero-healthcare-state-drug-regulators-impurity-testing/
https://www.mayoclinic.org/drugs-supplements/remdesivir-intravenous-route/description/drg-20503608













Dr Paul Alexander seems to have changed his mind quite quickly about this drug. Maybe there’s some back-pedalling going on.
https://palexander.substack.com/p/i-warn-again-about-remdesivir-all
Slam dunk, back of the net, hole in one, ten brownie points and an A*