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damon mcclure's avatar

Hi Geoff, would topically be safe?

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GeoffPainPhD's avatar

Hi Damon,

Why would anyone apply EDTA to their skin? 1998 paper:

“A clinical and histologic study in four patients revealed that apomorphine with EDTA caused severe subcutaneous nodules, histologically characterized by an inflammatory infiltrate with a large amount of eosinophils, indicating a cell-mediated allergic reaction. After withdrawal of EDTA, this allergic component completely disappeared, which was accompanied clinically by less extensive nodule formation with a softer consistency. It is therefore recommended that EDTA be excluded from apomorphine formulations.”

https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.870130113

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damon mcclure's avatar

It's being recommended by some of the more unusual supplement recommendations for heavy metal detox and I was curiousif it was safer.

Tired though and bed soon so thanks for the link

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