Abortion, Preeclampsia and Placenta Damage by Pfizer jabs are expected from the vial Endotoxin
Endotoxin adds to worry about the impact of mRNA, Lipid Nanoparticle chemicals and Bioburden in Pfizer jabs on Female reproductive system and the Foetus.
Analysis of VAERS Data
My good friend OpenVaet has done a deep dive into the acknowledged under-reported US VAERS database to 22 August 2022 and has produced an an excellent interactive guide to the impact of the Janssen, Moderna and Pfizer Covid19 jabs on Pregnancies.
Openvaet found 15 Maternal Deaths and 908 Foetal Deaths after Pfizer jabs by extracting symptoms in the text of VAERS reports. He found that 27.54 % of the reported Missed Pregnancies happened within 1 week of the jab.
Here I will concentrate on such Pfizer damage as it relates to Endotoxin content, which is expected to impact the Mother and Foetus within days of the jab.
Pfizer Spread the Pregnancy Danger Signals
To 15 April 2022, Pfizer reported that 1.3% of all Adverse Event cases after their jabs were from 17,156 Pregnant or Breastfeeding Women.
Image from DailyClout.
Pfizer spread these Adverse Events under 179 different descriptors under 2 main headings “Injury, Poisoning and Procedural Complications” and “Pregnancy, Puerperium and Perinatal conditions”, including case numbers as follows:
Maternal exposure during pregnancy 5,823
Exposure during pregnancy 524 Drug exposure before pregnancy 23
Abortion spontaneous 1,807 Abortion missed 114 Abortion early 18
Maternal exposure before pregnancy 329
Premature baby 181 Premature labour 64 Premature delivery 44 Threatened labour 14
Foetal Death 147
Foetal growth restriction 124
Foetal exposure during pregnancy 93
Foetal hypokinesia 76 Foetal distress syndrome 12
Haemorrhage in pregnancy 73
Uterine contractions during pregnancy 68
Pre-eclampsia 38 Uterine contractions abnormal 40
Ectopic pregnancy 67
Abortion 59
Stillbirth 56
Premature rupture of membranes 37 Preterm premature rupture of membranes 28
Uterine hypertonus 29
Postpartum haemorrhage 26
Premature separation of Placenta 25
Placental disorder 20
Anembryonic gestation 24
Oligohydramnios 14
HELLP (Hemolysis, Elevated Liver enzymes and Low Platelets) syndrome 13
Retroplacental haematoma 13
Decidual cast 10
and the list goes on and on and on.
Every vial of Pfizer Covid19 jab contains Endotoxin that can’t be removed, originating from the E coli bacteria essential to production.
Here I focus on how Endotoxin (LipoPolySaccharide, LPS) attacks the Human Female Reproductive system and the developing Placenta and Embryo.
Endotoxin Damage to the Placenta
First Trimester disruption of Placenta formation is caused by Endotoxin (LPS) and involves Mitogen-Activated Protein Kinase (MAPK) signaling pathway phosphorylation and resultant increase in IL-8 and IL-6. Endotoxin damages spiral artery remodeling, correlated with Monocyte Chemokine-1 (MCP-1), and down-regulates markers related to Extravillous Trophoblast invasion in Placentas.
In this Figure from Anton et al. MyD88 = Myeloid differentiation 88, IRAK = Interleukin Receptor Associated Kinase, TLR4 = Toll-Like Receptor 4, ERK = Extracellular signal-Regulated Kinase, TRAF6 = TNF Receptor Associated Factor 6, MAP3Ks = Mitogen-Activated Protein Kinase 3, MEK = MAPK Extracellular signal-regulated Kinase, p38 = p38 Mitogen-Activated Protein Kinase, JNK = c-Jun N-terminal Kinase.
As I mentioned earlier, TLR4 is a target for Covid19, Endotoxin and Nickel, all of which elevate IL-8.
Mouse models
show what injected Endotoxin does at a dose of 10 µg/kg Gestational Day (GD) 13, and 40 µg/kg LPS daily until GD16. Endotoxin significantly elevated the percentage of CD86 +, TNF-α+, IL-1β+ and iNOS+ dMφ (M1 subtype) but diminished the percentage of CD206 +, CD 163+, IL-10+ and Arg-1+ dMφ (M2 subtype) in pregnant mice.Endotoxin damages spiral artery remodeling, correlated with Monocyte Chemokine-1 (MCP-1), and down-regulates markers related to extravillous trophoblast invasion in Placentas.
Lethal Preeclampsia
Women suffering Preeclampsia, the major cause of maternal and perinatal Death, experience Hypertension, Proteinuria, Headache, Vomiting, Kidney and Liver dysfunction. They have increased number of circulating Leukocytes, Neutrophils, and serum levels of Tumor necrosis factor-α (TNF-α), Interleukin-6 (IL-6), C-reactive protein (CRP). This is found in Endotoxin poisoning.
Decidual macrophages (dMφ) are the second abundant immune cells in pregnancy and are adversely affected by Endotoxin, resulting in Miscarriage and Fetal Growth Restriction.
Women with Preeclampsia have lower levels of anti-inflammatory Interleukin 10 (IL10).
Han et al. (2021) collected Human Placentas to compare women with and without Preeclampsia. They showed that reduced α7 nicotinic AcetylCholine Receptor (α7nAChR) is involved in the Endotoxin response of exaggerated inflammation. The level of Choline Acetyltransferase (CHAT) was reduced in women with Preeclampsia and Endotoxin treated mice.
Chorioamnionitis caused by Endotoxin in Jabs
Preterm birth is a major cause of perinatal Death and long-term morbidity.
Endotoxin is routinely used to induce Preterm Birth and Sheep are a favoured test animal where the endotoxin can be administered via various routes, including injection into the Uterus or Amniotic Fluid.
Women and their developing foetuses suffer from Endotoxin induced Chorioamnionitis with Fever, Leukocytosis, Tachycardia, Uterine tenderness, and Preterm Rupture of Membranes.
Induced Abortion after Foetal Deformity
Here is a case of a woman jabbed with Pfizer who chose to terminate her pregancy at 25 week gestation because Heart Damage was detected in her developing Child.
She was injected with Oxytocin to induce the Abortion.
Conclusion
The Pfizer jab reports of worldwide Reduced Birthrate, Spontaneous Abortion, Stillbirth, Preeclampsia, Premature Birth, Maternal and Foetal Death can all be related to the toxic effects of the Endotoxin present in all vials.
https://openvaet.org/studies/vaers_fertility?currentLanguage=en
APPENDIX 2.1 Cumulative Number of Case Reports (Serious and Non-Serious, Medically Confirmed and Non Medically-Confirmed) from Post-Marketing Data Sources, Overall, by Sex, Country, Age Groups and in Special Populations and Summary Tabulation by Preferred Term and MedDRA System Organ Class BNT162B2 - ALL Reporting Period: Through 15-APR-2022 FOI-3727
Danielle Terricciato. 2016. https://dailyclout.io/moms-to-be-to-receive-medical-care-from-the-day-they-know-that-they-are-expecting/
Anton L, et al. Lipopolysaccharide induces cytokine production and decreases extravillous trophoblast invasion through a mitogen-activated protein kinase-mediated pathway: possible mechanisms of first trimester placental dysfunction. 2012. https://academic.oup.com/humrep/article/27/1/61/714411
Han X, et al. 2021. Stimulation of α7 Nicotinic Acetylcholine Receptor by Nicotine Suppresses Decidual M1 Macrophage Polarization Against Inflammation in Lipopolysaccharide-Induced Preeclampsia-Like Mouse Model. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113862/
Galinsky R, et al. 2013. The Consequences of Chorioamnionitis: Preterm Birth and Effects on Development. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606792/