SV40 immortalized Kidney Cells damaged by Endotoxin as found in every Pfizer Jab
mRNA Covid19 jabs damage every organ in the body and the effects on the Kidney are devastating. Kidney researchers study the mechanisms using SV40 immortalized cells, unfortunately ours are mortal.
As a member of the DailyClout team, I took a keen interest in the court ordered release of Pfizer trial data as it was posted and discussed in our weekly teleconferences.
In March 2021, Naomi Wolf of DailyClout announced the release of a one-page Micro-report on the clear and present danger signal that was found during the Pfizer trial.1
The DailyClout reporters found 69 patients, including one infant, suffered acute kidney injury or acute renal failure to February 2021. Half of the severe renal adverse events were reported within four days of vaccination and 67% of Kidney adverse event patients were women.
Pfizer reported massive numbers of Kidney injuries to April 2022, with case numbers:
Renal pain 1,745; Pollakiuria 888; Haematuria 815; Acute kidney injury 778; Dysuria 755; Urinary incontinence 689; Renal failure 625; Chromaturia 469; Renal impairment 372; Micturition urgency 349; Urinary retention 326; Cystitis noninfective 269; Nephrotic syndrome 259; Renal disorder 255; Incontinence 254; Proteinuria 236; Nephrolithiasis 221; Polyuria 216; Kidney infection 160; Urine odour abnormal 129; Renal colic 120; Chronic kidney disease 123; Urine abnormality 103; Nephritis 97; Anuria 90; Haemorrhage urinary tract 87; Tubulointerstitial nephritis 79; IgA nephropathy 78; Micturition disorder 74; Renal cyst 73; Oliguria 72; Glomerulonephritis 70; Nocturia 68; Renal infarct 64; Glomerulonephritis minimal lesion 52; Urinary tract disorder 42; Urinary tract inflammation 42; Nephropathy 39; Cystitis haemorrhagic 37; Leukocyturia 37; Renal function test abnormal 36; Urine flow decreased; Glomerulonephritis rapidly progressive 26; Azotaemia 25; Cystitis interstitial 24; Hydronephrosis 24; Choluria 19; Renal tubular necrosis 19; Calculus urinary 18; Renal haemorrhage 18; Renal vein thrombosis 18; Glomerulonephritis membranous 16; Renal injury 16; Stress urinary incontinence 16; Focal segmental glomerulosclerosis; Prerenal failure 15; Renal cancer 15; End stage renal disease 14; Renal artery thrombosis 14; Lupus nephritis 13; Cystitis-like symptom 12; Strangury 12; Albuminuria 11; Glomerulonephritis acute 11; Kidney enlargement 11; Nephritic syndrome 10; Renal ischaemia 10; Calculus bladder 9; Costovertebral angle tenderness 9; Haemoglobinuria 8; Micturition frequency decreased 8; Paroxysmal nocturnal haemoglobinuria 8; Renal atrophy 8; Renal neoplasm 8; Ureterolithiasis 8; Urinary tract obstruction 8; Kidney transplant rejection 8; Nephrosclerosis 7; Kidney congestion 5; Kidney malformation 4; Congenital cystic kidney disease; Oedematous kidney 3; Kidney fibrosis 2; Kidney rupture 2; Biopsy kidney abnormal 1; Kidney hypermobility 1; Single functional kidney 1 (this means total failure of 1 Kidney); Subacute kidney injury 1; Ultrasound kidney abnormal 1
And the list goes on - Pfizer had no interest in consolidating the people (not numbers) suffering Kidney damage that could prove fatal
Endotoxin in the jabs does the damage
In 1952 it was found that Rabbits pretreated with Cortisone suffered multiple organ damage, particularly in the Kidneys after they were given a single intravenous injection of Gram-negative Bacterial Endotoxin.2
In 1968 Starzl and coworkers reported tragic destruction of Human Kidneys due to suspected Endotoxin priming in 3 transplant patients.3
Endotoxin produces immediate damage to Mesangial cells (MC) which maintain the architecture and cellular communication and indirectly join in the glomerular filtration rate for the correct functioning of the glomerulus of our Kidneys.4
The researchers from Mexico and Germany used immortalized commercially available Mouse Kidney cells to show that some particular inflammatory cytokines, including the “Apex Cytokine” IL-1β and Interleukin 36β (IL-36β) were upregulated. This leads to NLRP3 inflammasome formation and the activation of the IL-17/IL-23 axis in Kidney tissue, which in turn induces an increase in the inflammatory and fibrotic factors in tubular epithelial cells that allow the formation of tubulointerstitial lesions (normally associated with Chronic Kidney disease).
They stained for IL-36β with a green dye (scale marker 20 micron).
Note the strong effect with a concentration of 100 picograms per mil.
Details of Endotoxin Harms to Kidneys
By 2012, with deeper understanding of the control of Cytokine release, there were efforts to develop drugs that might ameliorate the poisoning of multiple organs by Endotoxins.5
c-Fos/activator protein (AP)-1 controls the expression of these cytokines by binding directly to AP-1 motifs in the cytokine promoter regions.
January 2024 update
See a nice Substack paper by Dr Colleen Huber.6
A paper behind a paywall on proposed treatment to reduce Endotoxin Kidney damage by upregulating NAD(P)H Quinone Oxidoreductase 1 and Heme Oxygenase 1 via Aryl Hydrocarbon Receptor (AhR) and Nuclear erythroid 2–related factor 2 (Nrf2) in the kidneys to lessen inflammation.7
Joseph Gehrett, Barbara Gehrett, ; Chris Flowers and Loree Britt. 2023. Report 62: Acute Kidney Injury and Acute Renal Failure Following Pfizer mRNA COVID Vaccination. 33% of Patients Died. Pfizer Concludes, “No New Safety Issue.” https://dailyclout.io/report-62-acute-kidney-injury-and-acute-renal-failure-following-pfizer-mrna-covid-vaccination-33-of-patients-died-pfizer-concludes-no-new-safety-issue/
Thomas L and Good RA. 1952. The effect of cortisone on the Shwartzman reaction; the production of lesions resembling the dermal and generalized Shwartzman reactions by a single injection of bacterial toxin in cortisone-treated rabbits. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212064/
https://www.researchgate.net/publication/8711101_The_effect_of_cortisone_on_the_Shwartzman_reaction_the_production_of_lesions_resembling_the_dermal_and_generalized_Shwartzman_reactions_by_a_single_injection_of_bacterial_toxin_in_cortisone-treated_ra
Starzl TE, et al. 1968. Shwartzman Reaction after Human Renal Homotransplantation. https://www.nejm.org/doi/full/10.1056/NEJM196803212781202
Pelcastre-Rodriguez CG. 2023. MES SV40 Cells Are Sensitive to Lipopolysaccharide, Peptidoglycan, and Poly I:C Expressing IL-36 Cytokines. https://www.mdpi.com/1422-0067/23/19/11922
Miyazaki H, et al. 2012. The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice. https://bmcnephrol.biomedcentral.com/articles/10.1186/1471-2369-13-153
Dhulkifle H, et al. 2023. 6-Formylindolo(3,2-b)carbazole Dampens Inflammation and Reduces Endotoxin-Induced Kidney Injury via Nrf2 Activation. https://pubs.acs.org/doi/10.1021/acs.chemrestox.3c00002
This scientific information is in the public domain. How can the govt and regulators 1. not know about it and 2. then continue to promote boosters as govt policy? Here is great potential for another vaccine contaminant to cause public harm. Conscience and legal liability appear of no concern.